@page {
   margin: 1cm;
}

html, body {
   font-family: Helvetica, arial, sans-serif;
   font-size: 11pt;
   line-height: 1.3;
   background-color: white;
   color: black;
}

@media screen {
   html, body {
      padding: 1rem;
   }
}
@media print {
   html, body {
      padding: 0;
   }
}

body > *:first-child {
   margin-top: 0 !important;
}

body > *:last-child {
   margin-bottom: 0 !important;
}

a {
   color: #4183C4;
   text-decoration: none;
}

   a absent {
      color: #dc3545;
   }

   a anchor {
      display: block;
      padding-left: 2.5rem;
      margin-left: -2.5rem;
      cursor: pointer;
      position: absolute;
      top: 0;
      left: 0;
      bottom: 0;
   }

h1, h2, h3, h4, h5, h6 {
   margin: 1.4em 0 0.8em 0;
   padding: 0;
   font-weight: bold;
   cursor: text;
   -webkit-font-smoothing: antialiased;
   break-after: avoid-page;
}

   h1 + *, h2 + *, h3 + *, h4 + *, h5 + *, h6 + * {
      break-before: avoid-page;
   }

   h1:hover a.anchor, h2:hover a.anchor, h3:hover a.anchor, h4:hover a.anchor, h5:hover a.anchor, h6:hover a.anchor {
      text-decoration: none;
   }

   h1 tt, h1 code, h2 tt, h2 code, h3 tt, h3 code, h4 tt, h4 code, h5 tt, h5 code, h6 tt, h6 code {
      font-size: inherit;
   }

h1 {
   font-size: 2.4rem;
}

h2 {
   font-size: 1.8rem;
   padding-bottom: 0.2em;
   border-bottom: 1px solid #aaa;
}

h3 {
   font-size: 1.6rem;
}

h4 {
   font-size: 1.4rem;
}

h5 {
   font-size: 1.2rem;
}

h6 {
   font-size: 1.2rem;
   color: #666;
}

p, blockquote, ul, ol, dl, li, pre {
   line-height: 1.3;
}

ul {
   list-style-type: disc;
}

ol {
   list-style-type: decimal;
}

p, blockquote, ul, ol, dl, li, table, pre {
   margin: 0.6em 0;
}

hr {
   border: none;
   color: #ddd;
   height: 0.3em;
   padding: 0;
}

h1 + h2, h1 + h3, h1 + h4, h1 + h5, h1 + h6,
h2 + h3, h2 + h4, h2 + h5, h2 + h6,
h3 + h4, h3 + h5, h3 + h6,
h4 + h5, h4 + h6,
h5 + h6 {
   margin-top: 0;
}

 
a:first-child h1, a:first-child h2, a:first-child h3, a:first-child h4, a:first-child h5, a:first-child h6 {
  margin-top: 0;
  padding-top: 0;
}
 
h1 p, h2 p, h3 p, h4 p, h5 p, h6 p {
  margin-top: 0;
}

sub {
   vertical-align: sub;
}

sup {
   vertical-align: super;
}

small, sub, sup {
   font-size: smaller;
}

big {
   font-size: larger;
}

address, em, cite, dfn, var, i {
   font-style: italic;
}

strong, b {
   font-weight: bold;
}

kbd, samp {
   font-family: monospace;
}

address, footer, header, details, summary {
   display: block;
}

q {
   display: inline;
}

   q::before {
      content: open-quote;
   }

   q::after {
      content: close-quote;
   }


li p.first {
   display: inline-block;
}

ul, ol {
   padding-left: 2em;
}

   ul:first-child, ul:first-child, ol:first-child, ol:first-child {
      margin-top: 0;
   }

   ul:last-child, ul:last-child, ol:last-child, ol:last-child {
      margin-bottom: 0;
   }

dl dt {
   font-size: 1.2em;
   font-weight: bold;
   font-style: italic;
   padding: 0;
   margin: 1.2em 0 0.6em;
}

   dl, dl dt:first-child {
      padding: 0;
   }

      dl dt > :first-child {
         margin-top: 0;
      }

      dl dt > :last-child {
         margin-bottom: 0;
      }

      dl dd {
         margin: 0 0 1.2em;
         padding: 0 1.2em;
      }

         dl dd > :first-child {
            margin-top: 0;
         }

         dl dd > :last-child {
            margin-bottom: 0;
         }

blockquote {
   border-left: 0.3em solid #dee2e6;
   padding: 0 1.2em;
   color: #6c757d;
}

   blockquote > :first-child {
      margin-top: 0;
   }

   blockquote > :last-child {
      margin-bottom: 0;
   }

table {
   padding: 0;
   margin: 0.6em 0;
   border-collapse: collapse;
   /*break-inside: avoid-page; */
}

   table.altrows tr:nth-child(2n) {
      background-color: #f8f8f8;
   }

   table tr {
      background-color: white;
      margin: 0;
      padding: 0;
   }

   table thead tr th {
      text-align: center;
   }

      table tr th {
         font-weight: bold;
         background-color: #eee;
      }

      table tbody tr td.rowheader, table tfoot tr th.rowheader {
         font-weight: bold;
         background-color: #eee;
      }

      table tr td {
         text-align: left;
      }

      table tr th, table tr td {
         margin: 0;
         padding: 0.5em;
         border: 1px solid #aaa;
      }

         table tr th.text-left, table tr td.text-left {
            text-align: left;
         }

         table tr th.text-right, table tr td.text-right {
            text-align: right;
         }

         table tr th.text-center, table tr td.text-center {
            text-align: center;
         }

         table tr th.hc-inner.hc-c-first, table tr th.hc-last.hc-c-first, table tr td.hc-inner.hc-c-first, table tr td.hc-last.hc-c-first {
            border-left-width: 3px;
            border-left-style: double;
         }

         table tr th:first-child, table tr td:first-child {
            margin-top: 0;
         }

         table tr th:last-child, table tr td:last-child {
            margin-bottom: 0;
         }

         table tr th.color-red, table tr td.color-red {
            color: #ff0000;
         }

         table tr th.bg-color-red, table tr td.bg-color-red {
            background-color: rgba(255, 0, 0, 0.33);
         }

         table tr th.color-green, table tr td.color-green {
            color: #00ff00;
         }

         table tr th.bg-color-green, table tr td.bg-color-green {
            background-color: rgba(0, 255, 0, 0.33);
         }

         table tr th.color-blue, table tr td.color-blue {
            color: #0000ff;
         }

         table tr th.bg-color-blue, table tr td.bg-color-blue {
            background-color: rgba(0, 0, 255, 0.33);
         }

span.frame {
   display: block;
   overflow: hidden;
}

   span.frame > span {
      border: 1px solid #dee2e6;
      display: block;
      float: left;
      overflow: hidden;
      margin: 13px 0 0;
      padding: 7px;
      width: auto;
   }

   span.frame span img {
      display: block;
      float: left;
   }

   span.frame span span {
      clear: both;
      color: #343a40;
      display: block;
      padding: 5px 0 0;
   }

span.align-center {
   display: block;
   overflow: hidden;
   clear: both;
}

   span.align-center > span {
      display: block;
      overflow: hidden;
      margin: 13px auto 0;
      text-align: center;
   }

   span.align-center span img {
      margin: 0 auto;
      text-align: center;
   }

span.align-right {
   display: block;
   overflow: hidden;
   clear: both;
}

   span.align-right > span {
      display: block;
      overflow: hidden;
      margin: 13px 0 0;
      text-align: right;
   }

   span.align-right span img {
      margin: 0;
      text-align: right;
   }

span.float-left {
   display: block;
   margin-right: 13px;
   overflow: hidden;
   float: left;
}

   span.float-left span {
      margin: 13px 0 0;
   }

span.float-right {
   display: block;
   margin-left: 13px;
   overflow: hidden;
   float: right;
}

   span.float-right > span {
      display: block;
      overflow: hidden;
      margin: 13px auto 0;
      text-align: right;
   }

code, tt {
   margin: 0 2px;
   padding: 0 5px;
   white-space: nowrap;
   border: 1px solid #e9ecef;
   background-color: #f8f8f8;
   border-radius: 3px;
}

pre code {
   margin: 0;
   padding: 0;
   white-space: pre;
   border: none;
   background: transparent;
}

.highlight pre {
   background-color: #f8f8f8;
   border: 1px solid #aaa;
   line-height: 19px;
   overflow: auto;
   padding: 6px 10px;
   border-radius: 3px;
}

pre {
   background-color: #f8f8f8;
   border: 1px solid #aaa;
   line-height: 19px;
   overflow: auto;
   padding: 6px 10px;
   border-radius: 3px;
}

   pre code, pre pre tt {
      background-color: transparent;
      border: none;
   }

.lim-color-chip {
   display: inline-block;
   line-height: 1;
   margin: 0 0 2px 0;
   vertical-align: middle;
   border-radius: 3px;
   width: 0.9em;
   height: 0.9em;
   background: #f0f0f0;
}

.lim-error {
   color: #ff0000;
}

.lim-position-relative {
   position: relative;
}

.lim-position-absolute {
   position: absolute;
}

.lim-flex-centered {
   display: flex;
   align-items: center;
   justify-content: center;
}

.lim-fill {
   width: 100%;
   height: 100%;
}

.lim-multi-image {
   position: relative;
   overflow: hidden;
}

   .lim-multi-image .lim-image-color {
      object-fit: fill;
   }

   .lim-multi-image .lim-image-overlay {
      position: absolute;
      top: 0;
      left: 0;
   }

.lim-flex-row-wrap {
   display: flex;
   flex-wrap: wrap;
   break-inside: avoid-page;
}

.lim-graph-fitted-data.lim-container {
   display: flex;
   flex-direction: row;
   align-items: start;
   justify-content: start;
}

   .lim-graph-fitted-data.lim-container > .lim-figure {
      margin: 1em 0;
      padding: 1em;
   }

.lim-graph-fitted-data.lim-container.lim-fit-results {
   page-break-inside: avoid;
}

.lim-spacer-1cm {
   flex: 0 1 1cm;
}

.lim-wellplate-table * {
   -webkit-touch-callout: none;
   -webkit-user-select: none;
   -moz-user-select: none;
   -ms-user-select: none;
   user-select: none;
}

.lim-wellplate-table {
   margin: 0;
   border-spacing: 0;
   border-collapse: collapse;
   background-color: white;
   border: 1px solid #aaa;
}

   .lim-wellplate-table td, .lim-wellplate-table th {
      padding: 0;
      text-align: center;
      vertical-align: middle;
   }

   .lim-wellplate-table th {
      font-size: 1rem;
      padding: 0;
   }

   .lim-wellplate-table tr {
      background-color: white;
   }

   .lim-wellplate-table td, .lim-wellplate-table th {
      border: 1px solid #aaa;
   }

   .lim-wellplate-table thead tr th, .lim-wellplate-table tbody tr th {
      background-color: #eee;
   }

svg.lim-image-binary polygon,
svg.lim-image-binary path {
   stroke-width: 1mm;
}

.lim-no-page-break-inside {
   break-inside: avoid-page;
}

body > .lim-no-page-break-inside:first-child > h1,
body > .lim-no-page-break-inside:first-child > h2,
body > .lim-no-page-break-inside:first-child > h3,
body > .lim-no-page-break-inside:first-child > h4,
body > .lim-no-page-break-inside:first-child > h5,
body > .lim-no-page-break-inside:first-child > h6 {
   margin-top: 0;
}

body > figure,
body > .lim-no-page-break-inside > figure {
   margin: 1em 0 3em 0;
   break-inside: avoid-page;
}

figure > figcaption.lim-title {
   margin: 1.2em 0 0.8em 0;
   font-size: 1.2rem;
}

figure > figcaption.lim-subtitle {
   margin: 0.8em 0 0.2em 0;
   font-size: 1.2rem;
   color: #666;
}

table.simple {
   border: none;
   padding: 0;
   border-collapse: collapse;
}

   table.simple > * > tr {
      border: none;
      background-color: white;
      margin: 0;
      padding: 0;
   }

   table.simple:not(.no-olines) > thead > tr:first-child,
   table.simple:not(.no-olines) > tbody:first-child > tr:first-child {
      border-top: 1px solid #444;
   }

   table.simple:not(.no-olines) > tfoot > tr:last-child,
   table.simple:not(.no-olines) > tbody:last-child > tr:last-child {
      border-bottom: 1px solid #444;
   }

   table.simple:not(.no-ilines) > tbody > tr:not(:first-child) {
      border-top: 1px solid #eee;
   }

   table.simple:not(.no-ilines) > thead > tr:last-child,
   table.simple:not(.no-ilines) > tbody > tr.header {
      border-bottom: 1px solid #aaa;
   }

   table.simple:not(.no-ilines) > tfoot > tr:first-child > th {
      border-top: 1px solid #aaa;
   }

   table.simple > tbody > tr:nth-child(2n) {
      background-color: inherit;
   }

   table.simple > * > tr > th {
      background-color: white;
      font-weight: bold;
   }

   table.simple > tbody > tr > td.rowheader,
   table.simple > tfoot > tr > th.rowheader {
      font-weight: bold;
      background-color: white;
   }


   table.simple > * > tr > th,
   table.simple > * > tr > td {
      border: none;
      text-align: left;
      margin: 0;
      padding: 0.3em 1em;
   }

   table.simple > * > tr.header > th,
   table.simple > * > tr.header > td {
      padding-top: 0.5em;
      padding-bottom: 0.5em;
   }

   table.simple > * > tr > th:first-child,
   table.simple > * > tr > td:first-child {
      padding-left: 0;
   }


table.summary > tbody > tr {
   border: none;
}

   table.summary > tbody > tr:not(:last-child) {
      border-bottom: 1px solid #eee;
   }

   table.summary > tbody > tr > th,
   table.summary > tbody > tr > td {
      padding: 0.3em 1em;
      border: none;
   }

      table.summary > tbody > tr > td:first-child {
         font-weight: bold;
         padding-left: 0;
         padding-right: 2em;
      }

      table.summary > tbody > tr > td:last-child {
         padding-right: 0;
      } 

table.tight {
   border: 0;
   padding: 0;
   border-collapse: collapse;
}

   table.tight > * > tr {
      border: 0;
      background-color: white;
      margin: 0;
      padding: 0;
   }

      table.tight > * > tr:nth-child(2n) {
         background-color: inherit;
      }

      table.tight > * > tr > th {
         font-weight: bold;
      }

      table.tight > * > tr > th,
      table.tight > * > tr > td {
         border: 0;
         text-align: left;
         margin: 0;
         padding: 0;
      }


   table.tight.text-left > * > tr > td, 
   table.tight.text-left > * > tr > th {
      text-align: left;
   }

   table.tight.text-right > * > tr > td, 
   table.tight.text-right > * > tr > th {
      text-align: right;
   }

   table.tight.text-center > * > tr > td, 
   table.tight.text-center > * > tr > th {
      text-align: center;
   }

   table.tight.b-white > * > tr > td, 
   table.tight.b-white > * > tr > th {
      border: 1px solid #fff;
   }

   table.tight.b-gray-1 > * > tr > td, 
   table.tight.b-gray-1 > * > tr > th {
      border: 1px solid #f8f9fa;
   }

   table.tight.b-gray-2 > * > tr > td, 
   table.tight.b-gray-2 > * > tr > th {
      border: 1px solid #e9ecef;
   }

   table.tight.b-gray-3 > * > tr > td, 
   table.tight.b-gray-3 > * > tr > th {
      border: 1px solid #dee2e6;
   }

   table.tight.b-gray-4 > * > tr > td, 
   table.tight.b-gray-4 > * > tr > th {
      border: 1px solid #ced4da;
   }

   table.tight.b-gray-5 > * > tr > td, 
   table.tight.b-gray-5 > * > tr > th {
      border: 1px solid #adb5bd;
   }

   table.tight.b-gray-6 > * > tr > td, 
   table.tight.b-gray-6 > * > tr > th {
      border: 1px solid #6c757d;
   }

   table.tight.b-gray-7 > * > tr > td, 
   table.tight.b-gray-7 > * > tr > th {
      border: 1px solid #495057;
   }

   table.tight.b-gray-8 > * > tr > td, 
   table.tight.b-gray-8 > * > tr > th {
      border: 1px solid #343a40;
   }

   table.tight.b-gray-9 > * > tr > td, 
   table.tight.b-gray-9 > * > tr > th {
      border: 1px solid #212529;
   }

   table.tight.b-black > * > tr > td, 
   table.tight.b-black > * > tr > th {
      border: 1px solid #000;
   }

   table.tight.w-1 > * > tr > td, 
   table.tight.w-1 > * > tr > th {
      width: 1cm;
   }

   table.tight.h-1 > * > tr > td, 
   table.tight.h-1 > * > tr > th {
      height: 1cm;
   }

   table.tight.w-2 > * > tr > td, 
   table.tight.w-2 > * > tr > th {
      width: 2cm;
   }

   table.tight.h-2 > * > tr > td, 
   table.tight.h-2 > * > tr > th {
      height: 2cm;
   }

   table.tight.w-3 > * > tr > td, 
   table.tight.w-3 > * > tr > th {
      width: 3cm;
   }

   table.tight.h-3 > * > tr > td, 
   table.tight.h-3 > * > tr > th {
      height: 3cm;
   }

   table.tight.w-4 > * > tr > td, 
   table.tight.w-4 > * > tr > th {
      width: 4cm;
   }

   table.tight.h-4 > * > tr > td, 
   table.tight.h-4 > * > tr > th {
      height: 4cm;
   }

   table.tight.w-5 > * > tr > td, 
   table.tight.w-5 > * > tr > th {
      width: 5cm;
   }

   table.tight.h-5 > * > tr > td, 
   table.tight.h-5 > * > tr > th {
      height: 5cm;
   }

   table.tight.w-6 > * > tr > td, 
   table.tight.w-6 > * > tr > th {
      width: 6cm;
   }

   table.tight.h-6 > * > tr > td, 
   table.tight.h-6 > * > tr > th {
      height: 6cm;
   }

   table.tight.w-7 > * > tr > td, 
   table.tight.w-7 > * > tr > th {
      width: 7cm;
   }

   table.tight.h-7 > * > tr > td, 
   table.tight.h-7 > * > tr > th {
      height: 7cm;
   }

   table.tight.w-8 > * > tr > td, 
   table.tight.w-8 > * > tr > th {
      width: 8cm;
   }

   table.tight.h-8 > * > tr > td, 
   table.tight.h-8 > * > tr > th {
      height: 8cm;
   }

   table.tight.p-1 > * > tr > td, 
   table.tight.p-1 > * > tr > th {
      padding: 1px;
   }

   table.tight.p-x-1 > * > tr > td, 
   table.tight.p-x-1 > * > tr > th {
      padding-left: 1px;
      padding-right: 1px;
   }

   table.tight.p-y-1 > * > tr > td, 
   table.tight.p-y-1 > * > tr > th {
      padding-top: 1px;
      padding-bottom: 1px;
   }

   table.tight.p-2 > * > tr > td, 
   table.tight.p-2 > * > tr > th {
      padding: 2px;
   }

   table.tight.p-x-2 > * > tr > td, 
   table.tight.p-x-2 > * > tr > th {
      padding-left: 2px;
      padding-right: 2px;
   }

   table.tight.p-y-2 > * > tr > td, 
   table.tight.p-y-2 > * > tr > th {
      padding-top: 2px;
      padding-bottom: 2px;
   }

   table.tight.p-3 > * > tr > td, 
   table.tight.p-3 > * > tr > th {
      padding: 3px;
   }

   table.tight.p-x-3 > * > tr > td, 
   table.tight.p-x-3 > * > tr > th {
      padding-left: 3px;
      padding-right: 3px;
   }

   table.tight.p-y-3 > * > tr > td, 
   table.tight.p-y-3 > * > tr > th {
      padding-top: 3px;
      padding-bottom: 3px;
   }

   table.tight.p-4 > * > tr > td, 
   table.tight.p-4 > * > tr > th {
      padding: 4px;
   }

   table.tight.p-x-4 > * > tr > td, 
   table.tight.p-x-4 > * > tr > th {
      padding-left: 4px;
      padding-right: 4px;
   }

   table.tight.p-y-4 > * > tr > td, 
   table.tight.p-y-4 > * > tr > th {
      padding-top: 4px;
      padding-bottom: 4px;
   }

   table.tight.p-5 > * > tr > td, 
   table.tight.p-5 > * > tr > th {
      padding: 5px;
   }

   table.tight.p-x-5 > * > tr > td, 
   table.tight.p-x-5 > * > tr > th {
      padding-left: 5px;
      padding-right: 5px;
   }

   table.tight.p-y-5 > * > tr > td, 
   table.tight.p-y-5 > * > tr > th {
      padding-top: 5px;
      padding-bottom: 5px;
   }

   table.tight.p-6 > * > tr > td, 
   table.tight.p-6 > * > tr > th {
      padding: 6px;
   }

   table.tight.p-x-6 > * > tr > td, 
   table.tight.p-x-6 > * > tr > th {
      padding-left: 6px;
      padding-right: 6px;
   }

   table.tight.p-y-6 > * > tr > td, 
   table.tight.p-y-6 > * > tr > th {
      padding-top: 6px;
      padding-bottom: 6px;
   }

   table.tight.p-7 > * > tr > td, 
   table.tight.p-7 > * > tr > th {
      padding: 7px;
   }

   table.tight.p-x-7 > * > tr > td,
   table.tight.p-x-7 > * > tr > th {
      padding-left: 7px;
      padding-right: 7px;
   }

   table.tight.p-y-7 > * > tr > td, 
   table.tight.p-y-7 > * > tr > th {
      padding-top: 7px;
      padding-bottom: 7px;
   }

   table.tight.p-8 > * > tr > td, 
   table.tight.p-8 > * > tr > th {
      padding: 8px;
   }

   table.tight.p-x-8 > * > tr > td, 
   table.tight.p-x-8 > * > tr > th {
      padding-left: 8px;
      padding-right: 8px;
   }

   table.tight.p-y-8 > * > tr > td, 
   table.tight.p-y-8 > * > tr > th {
      padding-top: 8px;
      padding-bottom: 8px;
   }  
